2.2. Experimental apparatus
A schematic of the reactor setup is shown in Fig. 2. Two Chemyx Nexus 3000 syringe pumps (Stafford, TX) syringe pumps were used along with 10 mL glass gas-tight syringes (SGE, Victoria, Australia) to pump reagents M4MAA (1) and DMF-DMA (2) to the tee junction and through the reactor coil respectively. The tubing reactors used in the flow experiments were constructed using 1.59 mm outer diameter (OD) PTFE tubing with either a 1.0 mm or 0.25 mm inner diameter (ID), polyetheretherketone (PEEK) tee junctions, and were assembled using suitable nuts and ferrules (IDEX Health and Science). The polytetrafluorethylene (PTFE) reactor coil was immersed in a water bath that was pre-heated or pre-cooled to the desired reaction temperatures.