This experiment is used to understand the effects of physiological shear stress present in human fallopian tube on the cellular transformation and dissemination of malignant fallopian tube cells using Chemyx Fusion 6000-X Syringe Pump.
Description:
The Chemyx Fusion 6000-x syringe pump is used to pump viscous fluid consisting of methylcellulose and DMEM F12 (1:1) through a flow chamber to apply shear stress to healthy fallopian tube epithelial cells. The pump is set at a constant flow rate for 24 hours to pump viscous fluids that range from 0.007 to 2.06 Dyne/cm2.
From the tube to the ovaries: the role of shear stress on the origin of ovarian cancer
University of Michigan
Raneem Ahmad, Geeta Mehta
